In spite of major recent advances in DIPG molecular characterization, this body of knowledge has not yet translated into better treatments.To date,more than 250 clinical trials evaluating radiotherapy along with conventional cytotoxic chemotherapy as well as newer biologic agents,have failed to improve the dismal outcome when compared to palliative
Characterized by positive symptoms (such as changes in behavior or thoughts, including delusions and hallucinations), negative symptoms (such as apathy, anhedonia, and social withdrawal), and cognitive impairments, schizophrenia is a chronic, severe, and disabling mental disorder with late adolescence or early adulthood onset.Antipsychotics are the
TV shows on any athletic event make clear that those who want gold medals cannot dispense statistics.And the statistics more appealing to champions and coachers are the extreme order statistics, and in particular ANAL maximum (or minimum) values and records.The models in statistics of extremes are usually semi-parametric or even non-parametric in n
The contribution presents partial results of the research work on the biblical wisdom literature and highlights certain dimensions of justice, connected with Wisdom personified.Particular attention has been given to the development of the literary motif of the personification of wisdom in the texts considered and to the relationship between the wis